In 1871, Cyrus Keemer, an Ephrata resident, received Jesus Christ as his Lord and Savior under the ministry of a New Holland pastor, M.J. Humma. From this experience, the vision to establish a caring ministry in Ephrata was born. Even though, in 1872, there were only 100 dwellings and shops in Ephrata, a few faithful people laid the cornerstone for a building 32 by 42 feet in size on July 28, 1872. After they built and dedicated the building on December 2, 1872, they held revival services. From those bold Gospel proclamations, 36 people organized the First United Brethren Church. Twenty years later the church membership of 140 and Sunday School of 175 dedicated the completed construction of a new, larger, two-story building.

Despite difficult economic times, in 1933 the people of faith had vision to build a new facility that would not only meet their present needs, but the needs of future generations. The Education Building, which houses the current Sunday School rooms and offices, was completed in 1936. In 1946 the Evangelical and United Brethren Churches merged to form the Evangelical United Brethren Church. At this point the congregation prepared to initiate the second phase of their building project, a new sanctuary. They completed the chapel behind the sanctuary in 1949 and placed the cornerstone in 1950. By 1955 they dedicated the completed main sanctuary. This is the facility we still worship and minister out of today.

In 1997 major upgrades were made to the current building and in 1998 the church purchased a nearby sixty-acre farm for future growth. The farm house and land are used today for current ministry and special events as First Church looks to what God has planned for their future. The real story of First Church is not of how the facility itself developed, but how the people of faith sacrificed and gave to the church to perpetuate the ministry and mission of Jesus Christ.